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br A KCNJ mutation corresponding to an S L
2019-05-18
A KCNJ8 mutation, corresponding to an S422L mutation in the protein, was first identified in a 14-year-old girl with early repolarization [59], who suffered frequent VF attacks. KCNJ8 encodes Kir6.1, which has 2 transmembrane regions, and the KATP channel is composed of a complex of Kir6.1 or Kir6
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After overdrive pacing excitation that is one
2019-05-18
After overdrive pacing, excitation that is one lap behind (the second beat after the stimulus) is caused by several mechanisms. One is the prolonged conduction time that is longer than the TCL due to a long conduction pathway and/or slow conduction. The other is the dual-loop reentry [12]. The exci
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Assim a decis o de avan ar
2019-05-18
Assim, g-quadruplex decisão de avançar sobre Lima deve ser entendida antes como uma “fuga para frente” do que como desdobramento de um crescimento orgânico. Mas em seu momento, havia um genuíno receio em relação ao poder insurgente, já que a repercussão das ações senderistas na capital era amplifica
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In patients with systolic heart failure and a wide
2019-05-17
In patients with systolic heart failure and a wide QRS complex, cardiac resynchronisation therapy (CRT) using left ventricular (LV) pacing has been shown to enhance survival, reduce heart failure hospitalisation and enhance exercise capacity in patients with all Go 6976 of heart failure. The patien
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retinoid x receptor br Discussion The natural history of
2019-05-17
Discussion The natural history of PMF is characterized by the possibility of blastic transformation in approximately 20% of all the cases [9]. Several factors might predict leukemic transformation, including percentage of circulating blasts, low platelets count and the presence of an unfavorable
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Perhaps counter intuitively the most strategic tobacco contr
2019-05-17
Perhaps counter-intuitively, the most strategic tobacco control policies to reduce adolescent smoking and secondhand smoke exposure in LMICs may not be those targeting adolescents. Targeted campaigns can be expensive, and are unlikely to be as effective as the more affordable tobacco control policie
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National coverage trends were accelerated because
2019-05-17
National coverage trends were accelerated because of the contribution of trends in the two poorest quintiles. In middle-income countries, for example, the estimated increase in national trends was around 25% faster as a result of the contribution of poor populations. Increases in coverage in rural a
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Cardiologic examination and detailed analysis of lead rest E
2019-05-17
Cardiologic examination and detailed analysis of 12-lead rest ECG were performed by an experienced cardiologist (E.C.) and reevaluated by another independent cardiologist (S.R.). According to Groh et al., severe ECG abnormality included at least one of the following: rhythm other than sinus; PR inte
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The OptiVol Fluid Index OVFI
2019-05-17
The OptiVol Fluid Index (OVFI), which is derived from changes in intrathoracic impedance, can effectively assess HF by analyzing the changes in the intrathoracic impedance detected by the original OptiVol algorithm. Small et al. previously determined that a frequent and extended threshold crossing c
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Both breast cancer and MM cause osteolytic lesions inhibitin
2019-05-17
Both breast cancer and MM cause osteolytic lesions, inhibiting osteoblast differentiation and thereby tipping the balance in favour of osteoclastic activity. In contrast, prostate cancer predominantly causes osteoblastic bone disease. Interestingly, increased marrow adiposity has been associated wit
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Furthermore the difference in the mean S A interval
2019-05-17
Furthermore, the difference in the mean S–A interval between HB capture and non-capture in the 4 patients with conduction pattern 2 or 3 was only 20±4ms (range, 16–27ms), and was shorter than the HV interval after ablation in 3 patients (75%). By contrast, in patients with strictly AV nodal retrogra
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br Conclusions It is now clear that a number of
2019-05-17
Conclusions It is now clear that a number of QVDOPh are involved in inherited bradyarrhythmia. Recent genetic studies have demonstrated that inherited arrhythmia is attributable to many genes with diverse functions. While the precise underlying mechanisms remain to be elucidated; these genetic de
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br Materials and methods br Results br Discussion The presen
2019-05-17
Materials and methods Results Discussion The present study has demonstrated that the Wavelet discrimination algorithm is affected by myopotential interference, as evidenced by the large number of patients (55%) showing positive morphology change (defined as the percent-match score of the Wa
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To assess quality independent from quantity Imamura and
2019-05-17
To assess quality independent from quantity, Imamura and colleagues assessed dietary intake adjusted for 2000 kcal per day. An unfortunate consequence of this adjustment is that the role of unrestrained energy intake in the obesity and diabetes epidemics seems to be rendered obsolete. For example, i
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Infectious and parasitic diseases cause about half the
2019-05-16
Infectious and parasitic diseases cause about half the anaemia burden. Stevens and colleagues estimate that iron-amenable anaemia was about 50% in non-pregnant and pregnant women, and 42% in children in 2011. In addition to the contributions of malaria, schistosomiasis, hookworm infection, and HIV,
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