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Perhaps the greatest challenge however
2019-05-23
Perhaps the greatest challenge however, relates to the epidemiology of this disease and understanding the interactions that occur between the reservoir hosts (ie, monkeys), vectors, and human activities that enable transmission. Understanding these complex behavioral and ecological interactions will
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In summary we have established an
2019-05-23
In summary, we have established an animal model of human NB bone metastasis in which COX-2/PGE2 plays a critical role. We provide pre-clinical data supporting the use of COX-2 inhibitors in the treatment of bone metastases in NB. Conflict of interest statement Introduction Desmoplastic fibro
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br Las paradojas de un escritor norteamericano S
2019-05-22
Las paradojas de un escritor norteamericano Séptima novela de Hergesheimer, Tampico está considerada entre las menos artísticas que escribió. Tal vez el choque con la descarnada realidad del enclave petrolero enba puso en cuestión, hasta cierto punto, su vocación esteticista. El relato abunda en
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Chronic myelogenous leukemia blast crisis is highly
2019-05-22
Chronic myelogenous leukemia blast crisis is highly refractory to standard induction chemotherapy, with a response rate of less than 20–30% [12,13]. In patient\'s with Imatinib resistant disease Dastanib and Nilotinib can help achieve hematological response however neither drug has been reported to
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Aside from this report only two other studies of dexrazoxane
2019-05-22
Aside from this report, only two other studies of dexrazoxane use in adult AML patients have been published. In a series of seven patients with AML, Lemez and Maresova reported that the administration of dexrazoxane 30min before daunorubicin (dose 8-13x higher than daunorubicin) or mitoxantrone (dos
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We have recently completed a prospective randomized feasibil
2019-05-22
We have recently completed a prospective randomized feasibility study of de-escalated bisphosphonate treatment with intravenous pamidronate in patients with metastatic breast cancer to bone [7]. Here we report on an analysis utilizing data from this trial aimed at comparing BPI and FACT-BP and to co
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Describe la colonizaci n de Am
2019-05-22
Describe la colonización de América en términos de violencia, explotación y maltrato, una imposición que el poeta todavía siente en su presente, el legado de la colonialidad: A lo largo del texto, Pellicer alude al mito de Quetzalcóatl en relación StemRegenin 1 la invasión europea y la resistencia
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Si bien existen otras bases de
2019-05-21
Si bien existen otras bases de datos similares como Scielo y Dialnet, desde las cuales también se podría haber recuperado la documentación pertinente para este estudio, se estimó que redalyc representaba más adecuadamente el mapeo de la región, debido AEG 3482 que Scielo tiene un sesgo marcado haci
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br Methods This prospective study was
2019-05-21
Methods This prospective study was conducted at the Zekai Tahir Burak Woman\'s Health, Research and Education Hospital, Ankara, Turkey between April 2009 and August 2009. The study was approved by the local Ethics Committee of the hospital, and an informed consent was signed by all patients befor
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glutathione reductase In focal coronary spastic angina intra
2019-05-21
In focal coronary spastic angina, intravascular ultrasound was reported to detect intima–media complex thickening and an increased sonolucent zone [16,17], and OCT can detect intimal thickening with low lipid and calcium deposits [18], which are believed to reflect neointimal hyperplasia subsequent
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br To see how the quantity of osteosarcoma
2019-05-21
To see how the quantity of osteosarcoma in vitro studies developed overtime, we set out to systematically identify all the drugs that have been tested on osteosarcoma azilsartan medoxomil in vitro in the past two decades. A PubMed search strategy was compiled which can be found in Supplementary d
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Our findings show that primary prevention ICD
2019-05-21
Our findings show that primary prevention ICD recipients experienced an impaired QOL on vitality subscales, which were included in the physical health domain, compared to secondary prevention ICD recipients. Similarly, Berg et al. also found that ICD patients with a primary prevention indication had
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LQT can have numerous clinical manifestations ranging
2019-05-21
LQT1 can have numerous clinical manifestations, ranging from no symptoms to sudden cardiac death, which reflects the heterogeneity in channel dysfunction. Mutation type, location, and even a patient׳s ethnic background, age, and gender are critical factors that affect the pathophysiology of the dise
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br Alternans and arrhythmogenesis in
2019-05-21
Alternans and arrhythmogenesis in different clinical conditions APD alternans, whether spatially concordant or discordant, can produce arrhythmias. For example, spatially concordant alternans themselves can produce 2:1 conduction block, thereby initiating re-entry [48]. Nevertheless, discordant a
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A number of clinical studies have confirmed the beneficial
2019-05-21
A number of clinical studies have confirmed the beneficial effect of ranolazine in either prevention or treatment of AF. The first strong evidence was provided by MERLIN-TIMI 36 trial [the Metabolic Efficiency With Ranolazine for Less Ischemia in Non–ST-Elevation Acute Coronary Syndrome–Thrombolysis
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