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br Ocular surface squamous neoplasia OSSN
2019-05-23
Ocular surface squamous neoplasia (OSSN) has emerged as an important manifestation of the HIV epidemic, especially in sub-Saharan Africa. This region has not only gained the unenviable position of having the highest prevalence of OSSN, but patients with HIV tend to present with larger tumours and
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In conclusion describing a single case observation of a PV
2019-05-23
In conclusion, describing a single case observation of a PV-patient we have for the first time delivered the “proof of concept” that combination therapy with Rux and “low-dose” IFN is safe, tolerable and highly efficacious in PV, as evidenced by a rapid reduction in the JAK2V617F-allele burden in co
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Venous gangrene treatment is based on therapeutic anticoagul
2019-05-23
Venous gangrene treatment is based on therapeutic anticoagulation and thrombolytic therapy. Low-molecular weight heparin is a good choice for patients with active cancer and for pregnant women with good renal function, whereas heparin is used as an alternative in patients with poor renal function. M
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In patients with systolic heart
2019-05-23
In patients with systolic heart failure and a wide QRS complex, cardiac resynchronisation therapy (CRT) using left ventricular (LV) pacing has been shown to enhance survival, reduce heart failure hospitalisation and enhance exercise capacity in patients with all arecoline hydrobromide of heart fail
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br Mega cohort studies Remote monitoring collects a
2019-05-23
Mega-cohort studies Remote monitoring collects a wealth of data from large numbers of patients which are not subject to saturation or overwritten memory counters within any implantable device. These databases provide an opportunity to better understand system function, patient condition, and dise
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A dual chamber ICD was
2019-05-23
A dual-chamber ICD was then implanted and the optimal atrioventricular (AV) interval to obtain the lowest PG was adjusted to a sensed PV interval of 70ms/AV pace of 60ms using echocardiography. After 1 week, the LVOT-PG had decreased to 68mmHg (Fig. 2B); by 3 weeks, it had decreased to 26mmHg (Fig.
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order Octreotide acetate Cerrone et al reported that the mec
2019-05-23
Cerrone et al. reported that the mechanism of CPVT was due to delayed afterdepolarization‐induced triggered activity in a focal Purkinje network in a knock-in (RyR2) mouse [36]. In addition, chemical ablation of the RV endocardial cavity with Lugol׳s solution, which selectively destroys the Purkinje
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br Interpretation of identified genetic variants and genetic
2019-05-23
Interpretation of identified genetic variants and genetic counseling Although the current expert consensus statement recommends that comprehensive or BrS1 (SCN5A) targeted BrS genetic testing can be useful for genetic testing [63], not all the published SCN5A mutations in BrS have been subjected
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br LA REVISTA DEL EXILIO EN TANTO PROYECTO
2019-05-23
LA REVISTA DEL EXILIO EN TANTO PROYECTO CULTURAL Si bien existen estudios sobre la figura del exiliado —Agamben, Zuleta—, que consideran las variables históricas —Clara Lida y Pablo Yankelevich— y los esfuerzos de proporcionar corpus testimoniales con nuevas aproximaciones acerca del exilio, que
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To the best of our knowledge
2019-05-23
To the best of our knowledge, only one other group studied low-dose protracted oral clofarabine in MDS patients who failed hypomethylating agents. They studied 5mg (fixed dose) daily for 10 consecutive days of a 28-day cycle. All patients who were treated for 10 days had a greater than 25% drop in t
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Perhaps the greatest challenge however
2019-05-23
Perhaps the greatest challenge however, relates to the epidemiology of this disease and understanding the interactions that occur between the reservoir hosts (ie, monkeys), vectors, and human activities that enable transmission. Understanding these complex behavioral and ecological interactions will
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In summary we have established an
2019-05-23
In summary, we have established an animal model of human NB bone metastasis in which COX-2/PGE2 plays a critical role. We provide pre-clinical data supporting the use of COX-2 inhibitors in the treatment of bone metastases in NB. Conflict of interest statement Introduction Desmoplastic fibro
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br Las paradojas de un escritor norteamericano S
2019-05-22
Las paradojas de un escritor norteamericano Séptima novela de Hergesheimer, Tampico está considerada entre las menos artísticas que escribió. Tal vez el choque con la descarnada realidad del enclave petrolero enba puso en cuestión, hasta cierto punto, su vocación esteticista. El relato abunda en
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Chronic myelogenous leukemia blast crisis is highly
2019-05-22
Chronic myelogenous leukemia blast crisis is highly refractory to standard induction chemotherapy, with a response rate of less than 20–30% [12,13]. In patient\'s with Imatinib resistant disease Dastanib and Nilotinib can help achieve hematological response however neither drug has been reported to
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Aside from this report only two other studies of dexrazoxane
2019-05-22
Aside from this report, only two other studies of dexrazoxane use in adult AML patients have been published. In a series of seven patients with AML, Lemez and Maresova reported that the administration of dexrazoxane 30min before daunorubicin (dose 8-13x higher than daunorubicin) or mitoxantrone (dos
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